Total Thyroid Screen

This test analyses serum levels of...

This test analyses serum levels of TSH, total T4, free T4, free T3, anti-TG antibodies, and anti-TPO antibodies to assess central and peripheral thyroid function, as well as thyroid auto-immunity.

Test Type: Serum Blood Test (additional cost for obtaining blood sample)

Adrenal Stress Profile

• ANALYTES - Cortisol and DHEA

• REQUIREMENTS - 4 saliva samples (5ml) collected at specific times over 24-hour period (frozen)

A Comprehensive Tool to Asses the HPA Axis—Stress Response and Resiliency

The Adrenal Stress Profile (ASP) provides an assessment of the Hypothalamic-Pituitary-Adrenal (HPA) axis using carefully timed salivary samples of the hormones cortisol and DHEA. Salivary testing is an easy, non-invasive option to measure unbound, biologically active parent hormone levels.

Daily hassles, chronic pain, blood sugar dysregulation, work stressors, and poor relationship quality can alter the HPA axis. Imbalances in adrenal hormones can have a wide range of negative consequences that can adversely impact a patient's overall quality of life. The symptoms of HPA axis dysfunction can be vague, and are highly variable, but may include: fatigue, insomnia, weight gain, depression, GI complaints, and chronic pain. HPA axis dysfunction is associated with many conditions including:

• hypertension

• cardiovascular disease

• gastrointestinal and immune dysregulation

• diabetes and metabolic syndrome

• depression

• chronic fatigue

• persistent pain

• neurodegenerative disease and cognitive decline

Adrenal Stress Profile testing can reveal these HPA axis imbalances and provide direction for clinical intervention with targeted therapeutic treatments, such as nutrient support and/or adaptogens, stress management, behavioural modification, and lifestyle interventions.

Optional Add-on:

Cortisol Awakening Response (CAR)

• Two awakening samples to evaluate CAR

• CAR is a transient, immediate rise in cortisol upon awakening and is distinct from the diurnal rhythm. CAR reflects a person's ability to cope with anticipated challenges and their perception of control around chronic stress, providing insight into HPA axis resiliency.

GI Effects Comprehensive Stool Profile

The GI Effects Comprehensive Stool Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhoea, and constipation. This stool analysis utilises biomarkers such as faecal calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).4,5 In addition, Genova's GI Effects test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Gut microbes are codependent with one another and with their human host, and the health of one affects the other. A sizeable volume of research associates a dysbiotic, or imbalanced gut microbiome with multiple disease states both within and outside of the GI tract.2,3 The diverse metabolic activities of the microbiome ultimately impact the human host, and the activities of the human host ultimately affect the health of their microbiome.

Small Intestinal Bacterial Overgrowth (SIBO)

Requirements

• SIBO 2 Hr - Six fasting breath samples, taken at Baseline, 20 minutes, 40 minutes, 60 minutes, 90 minutes, and 120 minutes.

• SIBO 3 Hr - Eight fasting breath samples, taken at Baseline, 20 minutes, 40 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, and 180 minutes.

Uncover the Cause of Unexplained Abdominal Symptoms with Breath Testing

SIBO is a common clinical condition and can develop in a variety of patient populations.

Genova's SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the small intestine. Levels of Carbon Dioxide (CO2) are also measured in every sample for quality control purposes.

Symptoms of SIBO are non-specific, encompassing abdominal pain/distention, diarrhoea, and flatulence.

Conditions commonly associated with SIBO include:

• IBS

• IBD

• Coeliac Disease

• Diabetes

• Fibromyalgia

• Rosacea

• Parkinson's Disease

• Obesity

Risk factors for development of SIBO include structural/anatomic issues, motility disorders, organ system dysfunction, elderly age and various medications (recurrent antibiotics, PPIs) that alter the gut microflora populations.

One Day Hormone Check™

• ANALYTES - cortisol, DHEA, Melatonin, Oestradiol, Oestriol, Oestrione, Oestrone, Progesterone, Testosterone.

• REQUIREMENTS - 5 x 3ml saliva.

A 24-hr Salivary Hormone Test for Assessing Key Hormones

The One Day Hormone Check™ is a convenient salivary hormone test that evaluates unbound, bioavailable hormone levels over 24 hours. Specimens collected over 24 hours are examined for levels of oestradiol, oestrone, oestriol, progesterone, the progesterone/oestradiol ratio (P/E2), testosterone, cortisol, DHEA, and melatonin.

The One Day Hormone Check™ provides information about the impact that shifting hormone levels can have in men (andropause or male menopause) and women (perimenopause and menopause). It can reveal imbalances of primary sex hormones and how they relate to other hormones, such as DHEA, cortisol, and melatonin. Using hormone testing, clinicians can customise hormone and/or nutritional therapies and monitor therapy.

Patients with hormone imbalance may present with:

• Fatigue

• Weight loss or gain

• Menstrual irregularities

• Loss of libido

• Insomnia

• Changes in hair and skin

• Flushes

Dutch Plus (Comp + CAR)

PRECISION ANALYTICAL
Product Code: OMN15-V
Category: Hormones, Blood
Turn Around Time: 2 Days

This combined panel, which includes the DUTCH Complete and the DUTCH CAR (Cortisol Awakening Response), can help identify the root causes of hormone imbalances in men and women. The test analyses 35 different hormones; oestrogen, progesterone, testosterone, DHEA-S and cortisol along with their metabolites. It also measures daily free cortisol, the oxidative stress marker 8OHdG, melatonin, six organic acids and the CAR, which is an excellent snapshot of HPA axis function. A low CAR can be a result of an underactive HPA axis, psychological burnout, seasonal affective disorder (SAD), sleep issues, PTSD, chronic fatigue, chronic pain, hypertension, gastrointestinal issues, post-natal depression and autoimmune disease. An elevated CAR can be the result of an overactive HPA axis, anticipatory stress, glycaemic dysregulation, pain and depression. The DUTCH Complete and DUTCH CAR are both available as stand-alone tests.

TURNAROUND TIME: 12 WORKING DAYS

GI360 Complete

DOCTORS DATA

This impressive new system incorporates many of the existing popular features of the Comprehensive Stool Analysis with Parasitology which evaluates the status of beneficial bacteria, imbalanced commensal bacteria, pathogenic bacteria, parasites and yeasts. In addition to the PCR testing, if pathogenic cultures are identified, a sensitivity panel is provided to facilitate the selection of pharmaceutical or natural treatment agents. The efficiency of digestion and absorption is measured via faecal elastase, fat, carbohydrate, muscle and vegetable fibres whilst the biomarkers of calprotectin, lysozyme, lactoferrin, white blood cells and mucus can be used to assess inflammation.

The GI360™ can help to differentiate inflammation associated with inflammatory bowel disease (IBD) from that noted in irritable bowel syndrome (IBS). Humoral immune status of the gut is measured by secretory IgA (sIgA) while the assessment of short-chain fatty acids reflects overall gut health and microbiome balance.

Use this advanced system to identify the causes of gastrointestinal symptoms, autoimmune disease, joint pain, IBD, IBS, inflammation, food sensitivities, nutritional deficiencies and skin conditions.

OAT (Organic Acid Test)

GREAT PLAINS

The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with 76 markers. It provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behaviour disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

Great Plains Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.

If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test.

The Microbial Organic Acid Test is ideal for the follow-up to the OAT and is often recommended by practitioners looking for a specific abnormality, to monitor certain microbial imbalances, or to assess treatment efficacy.

TURNAROUND TIME: 30 WORKING DAYS

GPL-TOX (Toxic Organic Chemical Exposure)

GREAT PLAINS
Product Code: CMI41
Category: ENVIRONMENTAL TOXICITY

This combined panel, which includes the DUTCH Complete and the DUTCH CAR (Cortisol Awakening Response), can help identify the root causes of hormone imbalances in men and women. The test analyses 35 different hormones; oestrogen, progesterone, testosterone, DHEA-S and cortisol along with their metabolites. It also measures daily free cortisol, the oxidative stress marker 8OHdG, melatonin, six organic acids and the CAR, which is an excellent snapshot of HPA axis function. A low CAR can be a result of an underactive HPA axis, psychological burnout, seasonal affective disorder (SAD), sleep issues, PTSD, chronic fatigue, chronic pain, hypertension, gastrointestinal issues, post-natal depression and autoimmune disease. An elevated CAR can be the result of an overactive HPA axis, anticipatory stress, glycaemic dysregulation, pain and depression. The DUTCH Complete and DUTCH CAR are both available as stand-alone tests.

TURNAROUND TIME: 12 WORKING DAYS

Dutch Cycle Mapping with Complete

PRECISION ANALYTICAL
Product Code: HOR34
Category: Hormones

This panel provides a comprehensive assessment of sex hormones, adrenal function and the entire menstrual cycle. DUTCH Cycle Mapping delivers a clear understanding of the overall menstrual cycle by tracking and evaluating hormones throughout the month. Nine targeted oestrogen and progesterone measurements provide important details on a patient's hormone levels in the follicular, ovulatory and luteal phases of the cycle. The DUTCH Complete profile analyses 35 different hormones; oestrogen, progesterone, testosterone, DHEA-S and cortisol along with their metabolites. It also measures daily free cortisol, the oxidative stress marker 8OHdG, melatonin and six organic acids including markers for vitamin B12 (methylmalonate), vitamin B6 (xanthurenate), glutathione (pyroglutamate), dopamine (homovanillate), norepinephrine/epinephrine (vanilmandelate), and serotonin (5-hydroxyindoleacetate). This test is suitable for those with irregular cycles, unexplained infertility, luteal phase defects, PCOS, irregular cycles, PMS and PMDD, amongst many other hormone related conditions.

TURNAROUND TIME: 17 WORKING DAYS

SIBO Lactulose Test

BREATH TRACKERS

• Home breath test

SIBO is characterised by an increase in the number, or a change in, the type of bacteria found in the small intestine. The detection of hydrogen and methane in the breath after ingesting a substrate (lactulose) can help determine if SIBO is the cause of gastrointestinal symptoms such as diarrhoea, constipation, bloating, cramping, nausea, reflux, flatulence and belching.

Such symptoms, often non-specific and indistinguishable from those seen in irritable bowel syndrome (IBS) and other functional digestive disorders, can be the result of bacterial fermentation of short-chain carbohydrates in the small intestine. Risk factors for SIBO include achlorhydria, use of proton pump inhibitors (PPIs), pancreatitis, diabetic neuropathy, migrating motor complex (MMC) impairment, gastroenteritis, motility disorders, Crohn's Disease, IBS and Coeliac Disease. This simple test is non-invasive, performed at home and requires a 1-2-day preparatory diet and a 12-hours fasting period.

TURNAROUND TIME: 12 WORKING DAYS

Hair Toxic & Essential Elements

DOCTORS DATA

• Home hair test

Hair is essentially an excretory tissue rather than a functional tissue. Therefore, hair analysis provides important data that can be used in conjunction with symptoms and other laboratory values. It is an inexpensive and valuable screen for physiological excess, deficiency or maldistribution of elements. As protein is synthesised in the hair follicle, elements are permanently incorporated into the hair and represent a temporal record of element metabolism and toxic exposure. The levels of nutritional elements such as magnesium, zinc, copper, selenium and chromium correlate with levels in organs and other tissues whereas toxic elements may be 200-300 times more highly concentrated in hair than in blood and urine. Hair is generally the tissue of choice for detection of recent exposure to toxic elements such as arsenic, aluminium, cadmium, lead, antimony and mercury. This test may be useful for assessing toxic element exposure, excessive fish consumption, alopecia, depression, fatigue, malabsorption, hypertension, impaired glucose tolerance, kidney function, impotence, reduced testosterone, vision problems and Parkinson’s like symptoms.

TURNAROUND TIME: 12 WORKING DAYS

Thyroid Monitor And Vitamin Home Test

COUNTY PATHOLOGY

• Home finger prick blood spot test

Available in the UK and Republic of Ireland only, this comprehensive Thyroid Panel is a home test, utilising a finger prick, blood collection test and Free Return Postage. Brain fog, low energy and weight may have attributions related to Thyroid Performance. This panel combines recognised Thyroid Markers with the addition of markers  Vitamin Status, AutoImmunity and Inflammation. C-reactive protein), Ferritin (Iron), Vitamin D, Vitamin B12-Active, TSH (Thyroid Stimulating Hormone), Free T3, Free T4, TPO (Thyroid Peroxidase Antibodies), TBG (Thyroxine-binding globulin)

TURNAROUND TIME: 7 WORKING DAYS

HOME TEST: FINGER PRICK BLOOD SPOT

Mercury TRI Test

QUICKSILVER SCIENTIFIC
PRODUCT CODE: TEE14
CATEGORY: DETOXIFICATION
CATEGORY: ENVIRONMENTAL TOXICITY

The Mercury Tri-Test is the most comprehensive mercury test available. The Blood Metals Panel tests for 16 nutrient and toxic elements. Tri-Test for Dual Mercury Analysis – The Mercury Tri-Test is the only clinical test that utilizes blood, hair, and urine to measure excretion abilities and exposure of inorganic and methyl mercury.

• Exclusive Dual Mercury Analysis – Unlike common “Challenge Testing”, the Mercury Tri-Test separates methyl mercury (mostly from seafood or amalgam-based mercury) from inorganic mercury (the most toxic form) and measures each directly.

• No Need for Challenge Testing – Challenge testing can result in redistribution of metals in the organs. It can also have difficulties identifying long term toxicity and your unique mercury excretion capabilities. Tri-Test provides unprecedented information on exposure sources, body burden and ability to excrete each form of mercury.

• Nutrient + Toxic Metals Analysis – The Blood Metals Panel screens for a broad range of elements to show elevated exposure to toxic metals or imbalances of nutrient elements in whole blood.

• 16 Elements – Nutrient Elements: Calcium, Copper, Lithium, Magnesium, Manganese, Molybdenum, Selenium, Zinc. Potentially Toxic Metals: Antimony, Arsenic, Cadmium, Cobalt, Lead, Mercury, Silver, Strontium

TURNAROUND TIME: 19 WORKING DAYS

Dutch Cycle Mapping+ Plus

PRECISION ANALYTICAL
Product Code: HOR46
Category: Hormones

This is the most comprehensive combined DUTCH panel with Cortisol Awakening Response. DUTCH Cycle Mapping collects information on oestrogen and progesterone levels throughout the menstrual cycle whilst DUTCH Complete offers an extensive profile of sex and adrenal hormones along with 8OHdG, melatonin and six organic acids.

TURNAROUND TIME: 18 WORKING DAYS

Wellness360 Female Blood Test[ Venous Draw ]

UKAS-accredited medical laboratory
CATEGORY: Femail Overall health, Hormones, Blood
PRODUCT CODE: OMN15-V
TURNAROUND TIME: 2 DAYS

The Wellness 360 Female test is the most comprehensive test. Encompassing 58 biomarkers that cover a wide range of aspects, including hormones and vital organ function. Understanding the interconnections between stress, hormones, metabolism, vital organs, and key micronutrients can sometimes make it challenging to confidently pinpoint both the current issue and its most probable causes.

This test provides comprehensive reporting across all these areas, offering a holistic view of a client's health. It facilitates easier assessment of the best next steps for you to take. This test is ideal for complex cases involving multiple functional systems. It is also highly valuable as a starting point when the cause of a health issue is uncertain and a comprehensive investigation is needed. Additionally, it is perfect for individuals seeking comprehensive annual check-ups. Some of the areas of interest that this test covers include:

Menstruation issues, Exercise performance, Stress management, Age-related concerns, such as prostate health (for males) Energy regulation issues, Thyroid function, Liver function, Gallbladder function, Stomach/intestinal digestion and inflammation, Kidney function, Immune function and infection, Nutrient delivery (RBC function), Circulation and hydration, Micronutrient status (key vitamins and minerals), Blood sugar regulation, Lipid status.

Extra information:

Fasting for a blood test: In order to get the most accurate results, you should fast for 8 hours prior to taking a blood test. The best time to take your blood test is in the morning after having fasted overnight. Make sure you’re hydrated: Drink 2-3 litres of plain water the day before and at least 500 ml 1-2 hours prior to taking the test. Hydration can affect your results and how well blood will flow from the pinprick site.

Wellness360 Male Blood Test[ Venous Draw ]

UKAS-accredited medical laboratory
CATEGORY: Male Overall health, Hormones, Blood
PRODUCT CODE: OMN16-V
TURNAROUND TIME: 2 DAYS

The Wellness 360 Male test is the most comprehensive in the Omnos range, encompassing 59 biomarkers that cover a wide range of aspects, including hormones and vital organ function. Understanding the interconnections between stress, hormones, metabolism, vital organs, and key micronutrients can sometimes be challenging when trying to pinpoint both the current issue and its most probable causes with confidence. This test provides comprehensive reporting across all these areas, offering a holistic view of a client's health. It enables you to assess and determine the best next steps more easily.

This test is ideal for complex cases involving multiple functional systems. It is also highly valuable as a starting point when the cause of a health issue is uncertain and a comprehensive investigation is needed. Additionally, it is perfect for individuals seeking comprehensive annual check-ups. The test covers various areas of interest, including:

Sexual health function, Exercise performance, Stress management, Age-related concerns such as prostate health, Energy regulation issues, Thyroid function, Liver function, Gallbladder function, Stomach/intestinal digestion and inflammation, Kidney function, Immune function and infection, Nutrient delivery (RBC function), Circulation and hydration, Micronutrient status (key vitamins and minerals), Blood sugar regulation, Lipid status.

Extra information:

Fasting for a blood test: In order to get the most accurate results, you should fast for 8 hours prior to taking a blood test. The best time to take your blood test is in the morning after having fasted overnight. Make sure you’re hydrated: Drink 2-3 litres of plain water the day before and at least 500 ml 1-2 hours prior to taking the test. Hydration can affect your results and how well blood will flow from the pinprick site.